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Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes – affinity, specificity and regulation

TRAF1/2 and cIAP1/2 are members of the TNF receptor associated factor (TRAF) and the inhibitor of apoptosis (IAP) families, respectively. They are critical for both the canonical and the noncanonical NF-κB signaling pathways. Here we report the crystal structures of the TRAF2: cIAP2 and the TRAF1: T...

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Detalhes bibliográficos
Main Authors: Zheng, Chao, Kabaleeswaran, Venkataraman, Wang, Yaya, Cheng, Genhong, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855162/
https://ncbi.nlm.nih.gov/pubmed/20385093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.03.009
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