Bromination Pattern of Hydroxylated Metabolites of BDE-47 Affects Their Potency to Release Calcium from Intracellular Stores in PC12 Cells

BACKGROUND: Brominated flame retardants, including the widely used polybrominated diphenyl ethers (PBDEs), have been detected in humans, raising concern about possible neurotoxicity. Recent research demonstrated that the hydroxylated metabolite 6-OH-BDE-47 increases neurotransmitter release by relea...

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Autores principales: Dingemans, Milou M.L., Heusinkveld, Harm J., Bergman, Åke, van den Berg, Martin, Westerink, Remco H.S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Institute of Environmental Health Sciences 2010
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854729/
https://ncbi.nlm.nih.gov/pubmed/20368133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901339
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