Inhibition of Voltage-Gated Calcium Channels as Common Mode of Action for (Mixtures of) Distinct Classes of Insecticides

Humans are exposed to distinct structural classes of insecticides with different neurotoxic modes of action. Because calcium homeostasis is essential for proper neuronal function and development, we investigated the effects of insecticides from different classes (pyrethroid: (α-)cypermethrin; organo...

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Bibliographic Details
Published in:Toxicol Sci
Main Authors: Meijer, Marieke, Dingemans, Milou M.L., van den Berg, Martin, Westerink, Remco H.S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Voltage-Gated Calcium Channels and Insecticide Action
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833101/
https://ncbi.nlm.nih.gov/pubmed/24913802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu110
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