An anti-apoptotic peptide improves survival in lethal total body irradiation

Cell penetrating peptides (CPPs) have been used to deliver the anti-apoptotic Bcl-xL-derived BH4 peptide to prevent injury-induced apoptosis both in vitro and in vivo. Here we demonstrate that the nuclear localization sequence (NLS) from the SV40 large T antigen has favorable properties for BH4 doma...

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Main Authors: McDunn, Jonathan E., Muenzer, Jared T., Dunne, Benjamin, Zhou, Anthony, Yuan, Kevin, Hoekzema, Andrew, Hilliard, Carolyn, Chang, Katherine C., Davis, Christopher G., McDonough, Jacquelyn, Hunt, Clayton, Grigsby, Perry, Piwnica-Worms, David, Hotchkiss, Richard S.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854649/
https://ncbi.nlm.nih.gov/pubmed/19303399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.080
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