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Rosiglitazone modulates innate immune responses to Plasmodium falciparum and improves outcome in experimental cerebral malaria

For severe malarial syndromes such as cerebral malaria, adverse clinical outcomes are often immune-mediated rather than caused by the parasite directly; however, few therapeutics have been developed to modulate immunopathological host responses to infection. Here we report that PPARγ agonists (e.g....

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Bibliographische Detailangaben
Hauptverfasser: Serghides, Lena, Patel, Samir N., Ayi, Kodjo, Lu, Ziyue, Gowda, D. Channe, Liles, W. Conrad, Kain, Kevin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854576/
https://ncbi.nlm.nih.gov/pubmed/19392627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/598222
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