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C5 deficiency and C5a or C5aR blockade protects against cerebral malaria
Experimental infection of mice with Plasmodium berghei ANKA (PbA) provides a powerful model to define genetic determinants that regulate the development of cerebral malaria (CM). Based on the hypothesis that excessive activation of the complement system may confer susceptibility to CM, we investigat...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373845/ https://ncbi.nlm.nih.gov/pubmed/18426986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072248 |
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