C5 deficiency and C5a or C5aR blockade protects against cerebral malaria

Experimental infection of mice with Plasmodium berghei ANKA (PbA) provides a powerful model to define genetic determinants that regulate the development of cerebral malaria (CM). Based on the hypothesis that excessive activation of the complement system may confer susceptibility to CM, we investigat...

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Hlavní autoři: Patel, Samir N., Berghout, Joanne, Lovegrove, Fiona E., Ayi, Kodjo, Conroy, Andrea, Serghides, Lena, Min-oo, Gundula, Gowda, D. Channe, Sarma, J. Vidya, Rittirsch, Daniel, Ward, Peter A., Liles, W. Conrad, Gros, Philippe, Kain, Kevin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373845/
https://ncbi.nlm.nih.gov/pubmed/18426986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072248
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