Inhaled Nitric Oxide Reduces Endothelial Activation and Parasite Accumulation in the Brain, and Enhances Survival in Experimental Cerebral Malaria

The host immune response contributes to the onset and progression of severe malaria syndromes, such as cerebral malaria. Adjunctive immunomodulatory strategies for severe malaria may improve clinical outcome beyond that achievable with artemisinin-based therapy alone. Here, we report that prophylaxi...

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Autori principali: Serghides, Lena, Kim, Hani, Lu, Ziyue, Kain, Dylan C., Miller, Chris, Francis, Roland C., Liles, W. Conrad, Zapol, Warren M., Kain, Kevin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218025/
https://ncbi.nlm.nih.gov/pubmed/22110737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027714
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