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Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia: HIF-1-INDEPENDENT MECHANISMS

Hypoxia is a key determinant of tissue pathology during tumor development and organ ischemia. However, little is known regarding hypoxic regulation of genes that are directly involved in cell death or death resistance. Here we report the striking induction by severe hypoxia of the anti-apoptotic pro...

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Detalhes bibliográficos
Main Authors: Dong, Zheng, Venkatachalam, Manjeri A., Wang, Jinzhao, Patel, Yogendra, Saikumar, Pothana, Semenza, Gregg L., Force, Thomas, Nishiyama, Junichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854569/
https://ncbi.nlm.nih.gov/pubmed/11278985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M011774200
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