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Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia: HIF-1-INDEPENDENT MECHANISMS

Hypoxia is a key determinant of tissue pathology during tumor development and organ ischemia. However, little is known regarding hypoxic regulation of genes that are directly involved in cell death or death resistance. Here we report the striking induction by severe hypoxia of the anti-apoptotic pro...

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Autors principals: Dong, Zheng, Venkatachalam, Manjeri A., Wang, Jinzhao, Patel, Yogendra, Saikumar, Pothana, Semenza, Gregg L., Force, Thomas, Nishiyama, Junichiro
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854569/
https://ncbi.nlm.nih.gov/pubmed/11278985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M011774200
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