Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis

Benign neurofibromas and malignant peripheral nerve sheath tumors are serious complications of neurofibromatosis type 1. The epidermal growth factor receptor is not expressed by normal Schwann cells, yet is overexpressed in subpopulations of Nf1 mutant Schwann cells. We evaluated the role of EGFR in...

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Detalhes bibliográficos
Main Authors: Ling, Benjamin C., Wu, Jianqiang, Miller, Shyra J., Monk, Kelly R., Shamekh, Rania, Rizvi, Tilat A., DeCourten-Myers, Gabrielle, Vogel, Kristine S., DeClue, Jeffrey E., Ratner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854500/
https://ncbi.nlm.nih.gov/pubmed/15652750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2004.10.016
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