Brain Lipid Binding Protein in Axon-Schwann Cell Interactions and Peripheral Nerve Tumorigenesis

Loss of axonal contact characterizes Schwann cells in benign and malignant peripheral nerve sheath tumors (MPNST) from neurofibromatosis type 1 (NF1) patients. Tumor Schwann cells demonstrate NF1 mutations, elevated Ras activity, and aberrant epidermal growth factor receptor (EGFR) expression. Using...

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Detalhes bibliográficos
Main Authors: Miller, Shyra J., Li, Hongzhen, Rizvi, Tilat A., Huang, Yuan, Johansson, Gunnar, Bowersock, Jason, Sidani, Amer, Vitullo, John, Vogel, Kristine, Parysek, Linda M., DeClue, Jeffrey E., Ratner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149461/
https://ncbi.nlm.nih.gov/pubmed/12612091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.2213-2224.2003
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