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Mefloquine blockade of Pannexin1 currents: Resolution of a conflict

Our laboratory has reported potent block of Pannexin1 (Panx1) currents by the antimalarial quinine derivative mefloquine. However, other laboratories have found little or no mefloquine sensitivity of Panx1 currents or processes attributable to these channels. In order to resolve this issue, we have...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Iglesias, Rodolfo, Spray, David C., Scemes, Eliana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854254/
https://ncbi.nlm.nih.gov/pubmed/20218915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15419061003642618
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