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Mefloquine blockade of Pannexin1 currents: Resolution of a conflict

Our laboratory has reported potent block of Pannexin1 (Panx1) currents by the antimalarial quinine derivative mefloquine. However, other laboratories have found little or no mefloquine sensitivity of Panx1 currents or processes attributable to these channels. In order to resolve this issue, we have...

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Detalhes bibliográficos
Main Authors: Iglesias, Rodolfo, Spray, David C., Scemes, Eliana
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854254/
https://ncbi.nlm.nih.gov/pubmed/20218915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15419061003642618
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