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Homology Modelling of Human E1 Ubiquitin Activating Enzyme

Human E1 is a key player in protein ubiquitination, however the E1 structure is not available. In this paper, we describe the derivation of a human E1 structure using molecular modelling based on the crystal structure of S. cerevisiae E1 and M. Musculus E1. Key interactions between our E1 model and...

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Detalhes bibliográficos
Main Authors: Brahemi, Ghali, Burger, Angelika M., Westwell, Andrew D., Brancale, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853970/
https://ncbi.nlm.nih.gov/pubmed/20396627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157018010789869316
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