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Superoxide scavenging and Akt inhibition in myocardium ameliorate pressure overload-induced NF-κB activation and cardiac hypertrophy
Recent studies from our laboratory and others have shown that increases in cytoplasmic superoxide (O(2)(·−)) levels and Akt activation play a key role in agonist-stimulated NF-κB activation and cardiomyocyte hypertrophy in vitro. In this study, we tested the hypothesis that adenovirus (Ad)-mediated...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853899/ https://ncbi.nlm.nih.gov/pubmed/20103697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00202.2009 |
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