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The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

Tissue inhibitors of metalloproteinases (TIMPs) are widely distributed in the animal kingdom and the human genome contains four paralogous genes encoding TIMPs 1 to 4. TIMPs were originally characterized as inhibitors of matrix metalloproteinases (MMPs), but their range of activities has now been fo...

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Detalles Bibliográficos
Main Authors: Brew, Keith, Nagase, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853873/
https://ncbi.nlm.nih.gov/pubmed/20080133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.01.003
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