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Phage Display of Tissue Inhibitor of Metalloproteinases-2 (TIMP-2): IDENTIFICATION OF SELECTIVE INHIBITORS OF COLLAGENASE-1 (METALLOPROTEINASE 1 (MMP-1))
Tissue inhibitor of metalloproteinases-2 (TIMP-2) is a broad spectrum inhibitor of the matrix metalloproteinases (MMPs), which function in extracellular matrix catabolism. Here, phage display was used to identify variants of human TIMP-2 that are selective inhibitors of human MMP-1, a collagenase wh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173135/ https://ncbi.nlm.nih.gov/pubmed/21715326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253328 |
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