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Hyaluronan Synthase 2 (HAS2) Promotes Breast Cancer Cell Invasion by Suppression of Tissue Metalloproteinase Inhibitor 1 (TIMP-1)

Invasion and metastasis are the primary causes of breast cancer mortality, and increased knowledge about the molecular mechanisms involved in these processes is highly desirable. High levels of hyaluronan in breast tumors have been correlated with poor patient survival. The involvement of hyaluronan...

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Autors principals: Bernert, Berit, Porsch, Helena, Heldin, Paraskevi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234988/
https://ncbi.nlm.nih.gov/pubmed/22016393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.278598
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