Toll-Like Receptor-9 Agonist Inhibits Airway Inflammation, Remodeling and Hyperreactivity in Mice Exposed to Chronic Environmental Tobacco Smoke and Allergen

BACKGROUND: As passive environmental tobacco smoke (ETS) exposure in nonsmokers can increase both asthma symptoms and the frequency of asthma exacerbations, we utilized a mouse model, in which ovalbumin (OVA) + ETS induce significantly increased levels of eosinophilic airway inflammation and remodel...

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Detalhes bibliográficos
Main Authors: Song, Dae Jin, Min, Myung Goo, Miller, Marina, Cho, Jae Youn, Yum, Hye Yung, Broide, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853586/
https://ncbi.nlm.nih.gov/pubmed/19851071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000250437
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