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Allergen-Induced Coexpression of bFGF and TGF-β1 by Macrophages in a Mouse Model of Airway Remodeling: bFGF Induces Macrophage TGF-β1 Expression in vitro

BACKGROUND: Basic fibroblast growth factor (bFGF) is a cytokine that is mitogenic for fibroblasts and smooth muscle and may play a role in airway remodeling in asthma. We have used a mouse model of chronic ovalbumin (OVA) allergen-induced airway remodeling to determine whether bFGF and fibroblast gr...

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Bibliografski detalji
Glavni autori: Yum, Hye Young, Cho, Jae Youn, Miller, Marina, Broide, David H.
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997445/
https://ncbi.nlm.nih.gov/pubmed/21109744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000317213
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