Assessment of cholesteryl ester transfer protein inhibitors for interaction with proteins involved in the immune response to infection

The CETP inhibitor, torcetrapib, was prematurely terminated from phase 3 clinical trials due to an increase in cardiovascular and noncardiovascular mortality. Because nearly half of the latter deaths involved patients with infection, we have tested torcetrapib and other CETPIs to see if they interfe...

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Główni autorzy: Clark, Ronald W., Cunningham, David, Cong, Yang, Subashi, Timothy A., Tkalcevic, George T., Lloyd, David B., Boyd, James G., Chrunyk, Boris A., Karam, George A., Qiu, Xiayang, Wang, Ing-Kae, Francone, Omar L.
Format: Artigo
Język:Inglês
Wydane: The American Society for Biochemistry and Molecular Biology 2010
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853464/
https://ncbi.nlm.nih.gov/pubmed/19965592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002295
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