Assessment of cholesteryl ester transfer protein inhibitors for interaction with proteins involved in the immune response to infection

The CETP inhibitor, torcetrapib, was prematurely terminated from phase 3 clinical trials due to an increase in cardiovascular and noncardiovascular mortality. Because nearly half of the latter deaths involved patients with infection, we have tested torcetrapib and other CETPIs to see if they interfe...

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Detalhes bibliográficos
Main Authors: Clark, Ronald W., Cunningham, David, Cong, Yang, Subashi, Timothy A., Tkalcevic, George T., Lloyd, David B., Boyd, James G., Chrunyk, Boris A., Karam, George A., Qiu, Xiayang, Wang, Ing-Kae, Francone, Omar L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853464/
https://ncbi.nlm.nih.gov/pubmed/19965592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002295
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