Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450

Cytochromes P450 (CYPs) metabolize polyunsaturated long-chain fatty acids (PUFA-LC) to several classes of oxygenated metabolites. Through use of human recombinant CYPs, we recently showed that CYP1A1, -2C19, -2D6, -2E1, and -3A4 are mainly hydroxylases, whereas CYP1A2, -2C8, -2C9, and -2J2 are mainl...

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Autors principals: Lucas, Danièle, Goulitquer, Sophie, Marienhagen, Jan, Fer, Maude, Dreano, Yvonne, Schwaneberg, Ulrich, Amet, Yolande, Corcos, Laurent
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853439/
https://ncbi.nlm.nih.gov/pubmed/19965576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003061
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