Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue

Inhibitors of cyclooxygenase (COX)-2 prevent suppression of aquaporin-2 and reduce polyuria in the acute phase after release of bilateral ureteral obstruction (BUO). We hypothesized that BUO leads to COX-2-mediated local accumulation of prostanoids in inner medulla (IM) tissue. To test this, rats we...

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Detalhes bibliográficos
Main Authors: Nørregaard, Rikke, Jensen, Boye L, Topcu, Sukru Oguzkan, Wang, Guixian, Schweer, Horst, Nielsen, Søren, Frøkiær, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853392/
https://ncbi.nlm.nih.gov/pubmed/20147610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00336.2009
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