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Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice

Aquaporin-2 (AQP2) is the predominant vasopressin-regulated water channel in kidney connecting tubule (CNT) and collecting duct (CD) and is essential for renal regulation of body water balance. However, the relative role of AQP2 to urinary concentration in the CNT and CD segments is unknown. To exam...

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Библиографические подробности
Главные авторы: Rojek, Aleksandra, Füchtbauer, Ernst-Martin, Kwon, Tae-Hwan, Frøkiær, Jørgen, Nielsen, Søren
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421336/
https://ncbi.nlm.nih.gov/pubmed/16581908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511324103
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