Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice

Aquaporin-2 (AQP2) is the predominant vasopressin-regulated water channel in kidney connecting tubule (CNT) and collecting duct (CD) and is essential for renal regulation of body water balance. However, the relative role of AQP2 to urinary concentration in the CNT and CD segments is unknown. To exam...

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Bibliografiske detaljer
Main Authors: Rojek, Aleksandra, Füchtbauer, Ernst-Martin, Kwon, Tae-Hwan, Frøkiær, Jørgen, Nielsen, Søren
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421336/
https://ncbi.nlm.nih.gov/pubmed/16581908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511324103
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