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Effects of aging on B cell function
Ability to make an optimal immune response to vaccines and infectious agents declines with age in humans and animal models. Recent advances have shown intrinsic B cell defects in aged mice and humans, including decreases in Ig class switch recombination (CSR), activation-induced cytidine deaminase (...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853364/ https://ncbi.nlm.nih.gov/pubmed/19608393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.06.001 |
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