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Aging Impairs Murine B Cell Differentiation and Function in Primary and Secondary Lymphoid Tissues

Age-related changes in humoral immunity are responsible for the reduced vaccine responses observed in elderly individuals. Although aging has been shown to affect T cells, dendritic cells and macrophages and these effects significantly impact humoral responses, intrinsic alterations in B cells also...

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Detalhes bibliográficos
Main Authors: Frasca, Daniela, Blomberg, Bonnie B
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295082/
https://ncbi.nlm.nih.gov/pubmed/22396888
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