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Augmented Sodium Currents Contribute to the Enhanced Excitability of Small Diameter Capsaicin-Sensitive Sensory Neurons Isolated From Nf1+/− Mice

Neurofibromin, the product of the Nf1 gene, is a guanosine triphosphatase activating protein (GAP) for p21ras (Ras) that accelerates conversion of active Ras-GTP to inactive Ras-GDP. Sensory neurons with reduced levels of neurofibromin likely have augmented Ras-GTP activity. We reported previously t...

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Bibliografische gegevens
Hoofdauteurs: Wang, Yue, Duan, J.-H., Hingtgen, C. M., Nicol, G. D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853284/
https://ncbi.nlm.nih.gov/pubmed/20164394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01010.2009
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