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Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin.

1. Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin. The present study shows the capsazepine acts as a competitive antagonist of capsaicin. 2. Capsazepine (10 microM) reversibly reduced or abolished the current response to capsaicin (500 nM) of voltage-clamped dorsal...

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Détails bibliographiques
Auteurs principaux: Bevan, S., Hothi, S., Hughes, G., James, I. F., Rang, H. P., Shah, K., Walpole, C. S., Yeats, J. C.
Format: Artigo
Langue:Inglês
Publié: 1992
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907893/
https://ncbi.nlm.nih.gov/pubmed/1422598
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