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Amelioration of Enteric Neuropathology in a Mouse Model of Niemann-Pick C by Npc1 Expression in Enteric Glia
Niemann-Pick C (NPC) disease is an autosomal recessive, lethal, neurodegenerative disorder caused by mutations in NPC1. Using the glial fibrillary acidic protein (GFAP) promoter, we demonstrated previously that astrocyte-specific expression of Npc1 decreased neuronal storage of cholesterol in Npc1(−...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853225/ https://ncbi.nlm.nih.gov/pubmed/19472223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22126 |
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