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Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes)

The small freshwater teleost, medaka (Oryzias latipes), has a history of usage in studies of chronic toxicity of liver and biliary system. Recent progress with this model has focused on defining the medaka hepatobiliary system. Here we investigate critical liver function and toxicity by examining th...

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書誌詳細
主要な著者: Howarth, Deanna L., Law, Sheran H.W., Law, J. McHugh, Mondon, J.A., Kullman, Seth W., Hinton, David E.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853180/
https://ncbi.nlm.nih.gov/pubmed/19963001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.11.022
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