SINGLE NUCLEOTIDE POLYMORPHISMS INSIDE microRNA TARGET SITES INFLUENCE TUMOR SUSCEPTIBILITY

Single nucleotide polymorphisms (SNPs) associated with polygenetic disorders, such as breast cancer (BC), can create, destroy or modify microRNA (miRNA) binding sites; however, the extent to which SNPs interfere with miRNA gene regulation and affect cancer susceptibility remains largely unknown. We...

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Huvudupphovsmän: Nicoloso, Milena S., Sun, Hao, Spizzo, Riccardo, Kim, Hyunsoo, Wickramasinghe, Priyankara, Shimizu, Masayoshi, Wojcik, Sylwia E., Ferdin, Jana, Kunej, Tanja, Xiao, Lianchun, Manoukian, Siranoush, Secreto, Giorgio, Ravagnani, Fernando, Wang, Xuemei, Radice, Paolo, Croce, Carlo M., Davuluri, Ramana V., Calin, George A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853025/
https://ncbi.nlm.nih.gov/pubmed/20332227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3541
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