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SINGLE NUCLEOTIDE POLYMORPHISMS INSIDE microRNA TARGET SITES INFLUENCE TUMOR SUSCEPTIBILITY

Single nucleotide polymorphisms (SNPs) associated with polygenetic disorders, such as breast cancer (BC), can create, destroy or modify microRNA (miRNA) binding sites; however, the extent to which SNPs interfere with miRNA gene regulation and affect cancer susceptibility remains largely unknown. We...

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Detalhes bibliográficos
Main Authors: Nicoloso, Milena S., Sun, Hao, Spizzo, Riccardo, Kim, Hyunsoo, Wickramasinghe, Priyankara, Shimizu, Masayoshi, Wojcik, Sylwia E., Ferdin, Jana, Kunej, Tanja, Xiao, Lianchun, Manoukian, Siranoush, Secreto, Giorgio, Ravagnani, Fernando, Wang, Xuemei, Radice, Paolo, Croce, Carlo M., Davuluri, Ramana V., Calin, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853025/
https://ncbi.nlm.nih.gov/pubmed/20332227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3541
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