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HIF1A gene polymorphisms and human diseases: graphical review of 97 association studies

Hypoxia-inducible factors (HIFs) belong to a family of transcription factors (TF) responsive to a low O(2) availability, which is often a characteristic feature of solid tumors. The alpha subunit of the HIF heterodimer is O(2)-sensitive, and once stabilized in hypoxia, it functions as a master regul...

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Vydáno v:Genes Chromosomes Cancer
Hlavní autoři: Gladek, I, Ferdin, J, Horvat, S, Calin, GA, Kunej, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395341/
https://ncbi.nlm.nih.gov/pubmed/28165644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22449
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