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Rapamycin Regulates Endothelial Cell Migration through Regulation of the Cyclin-dependent Kinase Inhibitor p27(Kip1)

Rapamycin is a macrolide antibiotic that inhibits vascular smooth muscle cell proliferation and migration and that is used clinically on drug-eluting stents to inhibit in-stent restenosis. Although inhibition of cell migration is an asset in preventing restenosis, it also leads to impaired stent end...

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Autors principals: Moss, Stephanie C., Lightell, Daniel J., Marx, Steven O., Marks, Andrew R., Woods, T. Cooper
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852937/
https://ncbi.nlm.nih.gov/pubmed/20097763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066621
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