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Loss of Canonical Insulin Signaling Accelerates Vascular Smooth Muscle Cell Proliferation and Migration Through Changes in p27(Kip1) Regulation

Insulin resistance is associated with an accelerated rate of atherosclerosis. Vascular smooth muscle cell (VSMC) migration and proliferation are important components of atherosclerosis. To elucidate the effects of the loss of normal insulin receptor (IR) signaling on VSMC function, we compared the p...

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Bibliografski detalji
Glavni autori: Lightell, Daniel James, Moss, Stephanie Collier, Woods, Thomas Cooper
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037159/
https://ncbi.nlm.nih.gov/pubmed/21190963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0722
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