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Relative Resistance to Mammalian Target of Rapamycin Inhibition in Vascular Smooth Muscle Cells of Diabetic Donors

BACKGROUND: Diabetes mellitus is associated with an increased risk of cardiovascular disease. Intimal thickening, a component of cardiovascular disease, entails the proliferation and migration of vascular smooth muscle cells (VSMCs). Inhibition of the mammalian target of rapamycin (mTOR) blocks VSMC...

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Detalhes bibliográficos
Main Authors: Lightell, Daniel J., Woods, T. Cooper
Formato: Artigo
Idioma:Inglês
Publicado em: the Academic Division of Ochsner Clinic Foundation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603189/
https://ncbi.nlm.nih.gov/pubmed/23532775
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