Mutant Ferritin L-chains That Cause Neurodegeneration Act in a Dominant-negative Manner to Reduce Ferritin Iron Incorporation

Nucleotide insertions that modify the C terminus of ferritin light chain (FTL) cause neurodegenerative movement disorders named neuroferritinopathies, which are inherited with dominant transmission. The disorders are characterized by abnormal brain iron accumulation. Here we describe the biochemical...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Luscieti, Sara, Santambrogio, Paolo, Langlois d'Estaintot, Béatrice, Granier, Thierry, Cozzi, Anna, Poli, Maura, Gallois, Bernard, Finazzi, Dario, Cattaneo, Angela, Levi, Sonia, Arosio, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852932/
https://ncbi.nlm.nih.gov/pubmed/20159981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096404
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky