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Mutant L-Chain Ferritins that Cause Neuroferritinopathy Significantly Alter Ferritin Functionality and Iron Permeability
In mammals, the iron storage and detoxification protein ferritin is composed of two functionally and genetically distinct subunit types, H (Heavy) and L (Light). The two subunits co-assemble in various ratios, with a tissue specific distribution, to form shell-like protein structures of 24 subunits...
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| Udgivet i: | Metallomics |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800815/ https://ncbi.nlm.nih.gov/pubmed/31513212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9mt00154a |
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