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MicroRNA-27b Contributes to Lipopolysaccharide-mediated Peroxisome Proliferator-activated Receptor γ (PPARγ) mRNA Destabilization

Peroxisome proliferator-activated receptor γ (PPARγ) gained considerable interest as a therapeutic target during chronic inflammatory diseases. Remarkably, the pathogenesis of diseases such as multiple sclerosis or Alzheimer is associated with impaired PPARγ expression. Considering that regulation o...

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Hlavní autoři: Jennewein, Carla, von Knethen, Andreas, Schmid, Tobias, Brüne, Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852921/
https://ncbi.nlm.nih.gov/pubmed/20164187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066399
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