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PPARγ1 attenuates cytosol to membrane translocation of PKCα to desensitize monocytes/macrophages
Recently, we provided evidence that PKCα depletion in monocytes/macrophages contributes to cellular desensitization during sepsis. We demonstrate that peroxisome proliferator–activated receptor γ (PPARγ) agonists dose dependently block PKCα depletion in response to the diacylglycerol homologue PMA i...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064025/ https://ncbi.nlm.nih.gov/pubmed/17325208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605038 |
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