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Lewis Acid-Promoted Friedel-Crafts Alkylation Reactions with α-Ketophosphate Electrophiles

[Image: see text] The BF(3)·OEt(2)-promoted nucleophilic substitution of α-aryl-α-ketophosphates to afford α,α-diaryl ketone products is described. Electron-rich α-ketophosphates perform best, with electron-neutral and electron-poor substrates also tolerated. The reaction is tolerant of a range of a...

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Bibliografiset tiedot
Päätekijät: Smith, Austin G., Johnson, Jeffrey S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852482/
https://ncbi.nlm.nih.gov/pubmed/20235527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100410k
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