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Activation of the PI3 Kinase Pathway By Retinoic Acid Mediates Sodium/Iodide Symporter (NIS) Induction and Iodide Transport in MCF-7 Breast Cancer Cells
Iodide uptake in the thyroid and breast is mediated by the sodium/iodide symporter (NIS). NIS activation is utilized for radioiodide imaging and therapeutic ablation of thyroid carcinoma. NIS is expressed in more than 70% of breast cancers, but at a level insufficient for radioiodine treatment (1)....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852426/ https://ncbi.nlm.nih.gov/pubmed/19351850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3234 |
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