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The Sodium Iodide Symporter (NIS): Regulation and Approaches to Targeting for Cancer Therapeutics

Expression of the sodium iodide symporter (NIS) is required for efficient iodide uptake in thyroid and lactating breast. Since most differentiated thyroid cancer expresses NIS, β-emitting radioactive iodide is routinely utilized to target remnant thyroid cancer and metastasis after total thyroidecto...

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Detalhes bibliográficos
Main Authors: Kogai, Takahiko, Brent, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408573/
https://ncbi.nlm.nih.gov/pubmed/22750642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.06.007
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