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The Sodium Iodide Symporter (NIS): Regulation and Approaches to Targeting for Cancer Therapeutics

Expression of the sodium iodide symporter (NIS) is required for efficient iodide uptake in thyroid and lactating breast. Since most differentiated thyroid cancer expresses NIS, β-emitting radioactive iodide is routinely utilized to target remnant thyroid cancer and metastasis after total thyroidecto...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kogai, Takahiko, Brent, Gregory A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408573/
https://ncbi.nlm.nih.gov/pubmed/22750642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2012.06.007
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