RAGE Modulates Hypoxia/Reoxygenation Injury in Adult Murine Cardiomyocytes via JNK and GSK-3β Signaling Pathways

BACKGROUND: Advanced glycation end-products (AGEs) have been implicated in diverse pathological settings including diabetes, inflammation and acute ischemia/reperfusion injury in the heart. AGEs interact with the receptor for AGEs (RAGE) and transduce signals through activation of MAPKs and proapopt...

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Bibliographic Details
Main Authors: Shang, Linshan, Ananthakrishnan, Radha, Li, Qing, Quadri, Nosirudeen, Abdillahi, Mariane, Zhu, Zhengbin, Qu, Wu, Rosario, Rosa, Touré, Fatouma, Yan, Shi Fang, Schmidt, Ann Marie, Ramasamy, Ravichandran
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852407/
https://ncbi.nlm.nih.gov/pubmed/20404919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010092
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