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Porphyrin Binding and Distortion and Substrate Specificity in the Ferrochelatase Reaction: The Role of Active Site Residues

The specific insertion of a divalent metal ion into tetrapyrrole macrocycles is catalyzed by a group of enzymes called chelatases. Distortion of the tetrapyrrole has been proposed to be an important component of the mechanism of metallation. We present the structures of two different inhibitor compl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Karlberg, Tobias, Hansson, Mattias D., Yengo, Raymond K., Johansson, Renzo, Thorvaldsen, Hege O., Ferreira, Gloria C., Hansson, Mats, Al-Karadaghi, Salam
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852141/
https://ncbi.nlm.nih.gov/pubmed/18423489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.03.040
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