In Vivo and In Vitro Studies of Bacillus subtilis Ferrochelatase Mutants Suggest Substrate Channeling in the Heme Biosynthesis Pathway

Ferrochelatase (EC 4.99.1.1) catalyzes the last reaction in the heme biosynthetic pathway. The enzyme was studied in the bacterium Bacillus subtilis, for which the ferrochelatase three-dimensional structure is known. Two conserved amino acid residues, S54 and Q63, were changed to alanine by site-dir...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Olsson, Ulf, Billberg, Annika, Sjövall, Sara, Al-Karadaghi, Salam, Hansson, Mats
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12081974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.14.4018-4024.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!