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One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

Recently discovered bacterial homologues of eukaryotic pentameric ligand-gated ion channels, such as the Gloeobacter violaceus receptor (GLIC), are increasingly used as structural and functional models of signal transduction in the nervous system. Here we present a one-microsecond-long molecular dyn...

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Detalles Bibliográficos
Main Authors: Nury, Hugues, Poitevin, Frédéric, Van Renterghem, Catherine, Changeux, Jean-Pierre, Corringer, Pierre-Jean, Delarue, Marc, Baaden, Marc
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852019/
https://ncbi.nlm.nih.gov/pubmed/20308576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001832107
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